英文名称

CAS NO.

化学结构式/Structure

适应症Indication

Vcare Code

Upadacitinib（ABT-494）
乌帕替尼

1310726-60-3

类风湿关节炎
JAK

387-1

关键中间体/Intermediate Name

CAS NO.

化学结构式/Structure

生产规模Current Scales

Vcare Code

(3R,4S)-3-(2-Bromoacetyl)-4-ethyl-1-pyrrolidinecarboxylic acid phenylmethyl ester

1428243-26-8

>50kg

568-1

N-Tosyl-5-bromo-4,7-diazaindole

1201186-54-0

>50kg

569-1

Carbamic acid, N-​[5-​[(4-​methylphenyl)​sulfonyl]​-​5H-​pyrrolo[2,​3-​b]​pyrazin-​2-​yl]​-​, 1,​1-​dimethylethyl ester

1201187-44-1

>50kg

569-100

Carbamic acid, N-​[5-​[(4-​methylphenyl)​sulfonyl]​-​5H-​pyrrolo[2,​3-​b]​pyrazin-​2-​yl]​-​, ethyl ester

1869118-24-0

>50kg

569-200